Biochemical staging of tau pathology

Stage 1 is characterized by the presence of tangles in the brain area which is the most vulnerable to tau pathology, namely the transentorhinal cortex (Brodmann area 35).

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease. Delacourte et al. Neurology. 1999 Apr 12;52(6):1158-65.

1. Stage 0

1. Stage1       

• Stage 2
• Stage 3
• Stage 4
• Stage 5
• Stage 6
• Stage 7
• Stage 8
• Stage 9
• Stage 10