Alzheimer
Brain diseases
Research
Tau
APP
Abeta
VCDN group
flag

Aging

ALS

ALS/PDC Guam
AGD
Bri
CBD
DLDH
DM1
Down S
GSS
FTD
FTDP-17
Huntington
Hallenvorden
IBM
Lewy BD
MSA
NPiD c
Parkinson D Guadeloupe
Parkinson
Dementia  in Parkinson 
Pick
Prion
PSP
PEP
Semantic  D
SSP
  ToD

 

APP metabolism and function
Primary structure, sequence and functional regions
Cartoon on the structure
APP splicing
Mutations
Cascade hypothesis
APP & cholinergy
Links between APP and neurodegeneration
Abeta map
APP Carboxy terminal fragments a and b stubs
 
Cleavage of APP, production of APP-CTFs and Abeta
alpha secretase cleavage
beta secretase (BACE, ...)
gamma secretase     and       PS1
sa-APP,a possible neuroprotectant
RIP: regulated intramembrane proteolysis 
APP- Tau interaction 
 
Other molecular aspects 
Alzheimer
Flag
Research
Tau
APP
Ab
 
ApoE
 
catenin
 
NSE
 
Parkin 
Pin1 
Presenilins,
Proteasome
Synuclein 
 
 
Ubiquitin
 
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