Alzheimer
Brain dis
eases
Research
Tau
APP
A
beta
VCDN group
Aging
A
LS
ALS/PDC Guam
A
GD
Bri
C
BD
DLDH
DM1
Down S
GSS
F
TD
FTDP-17
H
untington
Hallenvorden
IBM
L
ewy BD
MSA
NPiD c
Parkinson D Guadeloupe
Parkinson
Dementia in Parkinson
Pick
Prion
P
SP
PEP
Semantic D
SSP
ToD
APP metabolism and function
Primary structure, sequence
and functional regions
Cartoon on the structure
APP splicing
Mutations
Cascade hypothesis
APP & cholinergy
Links between APP and neurodegeneration
Abeta map
APP Carboxy terminal fragments
,
a
and
b
stubs
Cleavage of APP, production of APP-CTFs and Abeta
alpha secretase cleavage
beta secretase (BACE, ...)
gamma secretase
and
PS1
s
a
-APP,a possible neuroprotectant
RIP: regulated intramembrane proteolysis
APP- Tau interaction
Other molecular aspects
Alzheimer
Research
Tau
APP
A
b
ApoE
catenin
NSE
Parkin
Pin1
Presenilins
,
P
roteasome
Synuclein
Ubiquitin
Accueil
Liens vers sites apparentés
Lexique
Map of site
Plan du site